Bone metabolism
| Product name | NTX-Urine (Osteomark®)N-Terminal Telopeptide of Type I Collagen  | |||||||||
| Cat-Nr. | 9006 | |||||||||
| Range | 20 - 3000 nM BCE | |||||||||
| Sensitivity | 20 nM BCE (value not corrected for creatinine) | |||||||||
| Incubation time | 2 hours | |||||||||
| Sample volume | 25 µl | |||||||||
| Sample type | Urine, cell culture | |||||||||
| Sample preparation | Collect second void of morning urine or 24 hours urine without adding preservatives. Fasting sample collection is not required. Samples are stable at room temperature for 24 hours or refrigerated at 2-8 °C for up to 72 hours. Longer storage at -20°C. Stable up to 3 freeze and thaw cycles. | |||||||||
| Reference values | nmol Bone Collagen Equivalents/l (nM BCE) per mmol Creatinine/l = nM BCE / mM Creatinine
Reference values from children are available. | |||||||||
| Species | Human, dog, porcine, rat, bovine and rhesus macaque | |||||||||
| Tests | 96 Tests | |||||||||
| Method | ELISA | |||||||||
| Intended use | Osteomark® NTX-Urine test is used for the quantitative measured of cross-linked N-telopeptides of type I collagen in urine. The NTX molecule is bone specific due to the unique amino acid sequences of the cross-linked alpha-2 (I) N- telopeptide. Release of the NTX molecule is mediated by osteoclasts. Elevated levels of NTX indicate elevated bone resorption. NTX-levels are used for: • monitoring of antiresorptive therapy in osteoporosis • Paget’s disease. • monitoring and early detection of bone metastasis. | |||||||||
| Product informations | Kit Instructions (PDF 259,2 kB) Cross-reaction all species (PDF 74,6 kB) Bone & Cartilage Metabolism (PDF 1,8 MB) Children reference Values (PDF 39,8 kB) Cell culture (PDF 92,6 kB) |
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tecomedical总部位于瑞士的TECOmedical Group在德国，法国和比荷卢三国设有子公司，是医学和兽医诊断，生物安全和环境测试领域体外专业测试系统的领先提供商。此外，我们与意见领袖合作开发或评估新的测试系统，或为制药，CRO和研究组织提供服务。
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