ELISA Complement Activity Analysis

Product name	Complement factor H
Cat-Nr.	A040
Range	6 – 230 ng/mL
Sensitivity	3.9 ng/mL (Detection limit)LOD 3.15 ng/mLLLOQ 4.64 ng/mL
Incubation time	2.5 hours
Sample volume	10 µl (dilution 1:5000)
Sample type	Serum, EDTA-Plasma Do not use hemolyzed, hyperlipemic, heat-treated or contaminated samples
Sample preparation	Samples are stable for 4 hours at 4°C, for longer storage keep at -70°C Avoid multiple freeze-thaw cycles
Reference values	Serum – 108 to 510 µg/mL EDTA Plasma – 138 to 489 µg/mL
Species	Human
Cross reaction	Cross-reactivities for other species or proteins/peptides has not been tested
Tests	96
Method	ELISA
Intended use	Complement factor H (CFH) is the first regulatory protein of the alternative pathway of the complement system. Factor H regulates complement both in fluid phase and on cellular surfaces. Genetic analyses reveal a clear association of CFH with different human diseases. Mutations on Factor H result in pathology involving complement activation: aHUS Age-related macular degeneration Dense deposit disease Factor H is a direct modulator of cellular functions by binding to receptors: influences cellular interaction phagocytosis antimicrobial activities Complement factor H (CFH) is the first regulatory protein of the alternative pathway of the complement system. Factor H regulates complement both in fluid phase and on cellular surfaces. Genetic analyses reveal a clear association of CFH with different human diseases. Mutations on Factor H result in pathology involving complement activation: aHUS Age-related macular degeneration Dense deposit disease Factor H is a direct modulator of cellular functions by binding to receptors: influences cellular interaction phagocytosis antimicrobial activities
Product informations	Kit Instructions (PDF 479,3 kB) Cross-reaction all species (PDF 70,3 kB)