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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
tecomedical/Reagents Complement Analysis/1/A600
产品编号:A600
市  场 价:¥0.00
场      地:美国(厂家直采)
产品分类: 其它>配件>计数测量>
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品      牌: tecomedical
公      司:tecomedical
公司分类:
tecomedical/Reagents Complement Analysis/1/A600
商品介绍

Reagents Complement Analysis

Product name

Cobra Venom Factor

Cobra Venom Factor (CVF), sometimes referred to as C3b (Cobra), is the non-toxic, complement-activating component of cobra venom. Like naturally occurring human C3b, CVF forms a complex, or convertase, with complement components Factor B and Factor D. This CVFBbD convertase is capable of activating C3 in a wide variety of species via the alternative complement pathway. CVFBbD convertase is Factor H resistant and is therefore not blocked through the activity of Factor I or CR1 and can convert nearly 100% of the C3 to C3 and C5 fragments. Levels of iC3b, C3a, SC5b-9, C5a and the Factor B cleavage product Bb are all extremely high in CVF treated sera.

Cat-Nr.A600
Intended use

Specifications: Volume: 1.0 ml Activity: ≥ 350 units/vial Form: liquid Species: Naja naja kaouthia Storage: at or below -70°C Purity: > 95% by SDS-Page Protein Concentration: approximately 1.0 mg/mlApplications: This product has been used in an experimental setting to deplete complement activity in vitro and in vivo.References:

  • Agarwal, Szalai, A., The Arthus Reaction in Rodents: Species Specific Requirement of Complement, J. Immunol 164:463-468 (2000).
  • Vandenberg, C.W., et al., In Vivo Anti-complementary activities of the cobra venom factros form Naja and Naja haje, J. Immunol. Methods. 13(6):2870294, (1991).
  • Rajasinghe, H. et al., Key role of the alternative pathway in hyperacute rejection of rat hearts transplanted into fetal sheep, Transplantation. 63(3), 407-426 (1996).
  • Koymada, N. Bach, F., Transient complement inhibition plus T Cell immuno-suppression induces long term survival of mouse to rat cardiac xenografts, Transplantation. 6(9)1210-1215 (1998).

Product informations
Hemocompatibility Protocols (PDF 6,2 MB)

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tecomedical总部位于瑞士的TECOmedical Group在德国,法国和比荷卢三国设有子公司,是医学和兽医诊断,生物安全和环境测试领域体外专业测试系统的领先提供商。此外,我们与意见领袖合作开发或评估新的测试系统,或为制药,CRO和研究组织提供服务。

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